|
Gene symbol | Protein name | Phosphorylation type | Localization | Reference |
|
Kinases | | | |
SRC | Proto-oncogene tyrosine- | Tyr | nonreceptor | [23, 30, 31] |
protein kinase Src |
CSK | c-src tyrosine kinase | Tyr | nonreceptor | [24, 32, 33] |
FYN | Tyrosine-protein kinase Fyn | Tyr | nonreceptor | [34–36] |
ABL1 | Abl1 | Tyr | nonreceptor | [37, 38] |
SYK | Tyrosine protein kinase SYK | Tyr | nonreceptor | [39, 40] |
PTK2B | Protein-tyrosine kinase 2-beta | Tyr | nonreceptor | [41–43] |
FER | Tyrosine-protein kinase Fer | Tyr | nonreceptor | [44] |
EGFR | Epidermal growth factor receptor | Tyr | Receptor | [45] |
cMET/HGF | Hepatocyte growth factor receptor | Tyr | Receptor | [46] |
PRKCA | Protein kinase C alpha type | Ser/Thr | nonreceptor | [47] |
PRKACA | cAMP-dependent protein | Ser/Thr | nonreceptor | [48, 49] |
Kinase catalytic subunit alpha |
ROCK1 | Rho-associated, coiled-coil | Ser/Thr | nonreceptor |
[50] |
containing protein kinase 1 |
PRKCD | Protein kinase C delta type | Ser/Thr | nonreceptor | [51, 52] |
CSNK1E | Casein kinase I isoform epsilon | Ser/Thr | nonreceptor | [53] |
CSNK2A1 | Casein kinase 2 | Ser/Thr | nonreceptor | [54] |
PAK1 | Serine/threonine-protein kinase PAK 1 | Ser/Thr | nonreceptor | [55–57] |
MAPK8 | JNK | Ser/Thr | nonreceptor | [58] |
PRKD1 | Protein kinase D1 | Ser/Thr | nonreceptor | [59] |
PRKCI | Atypical protein kinase C-lambda/iota | Ser/Thr | nonreceptor | [60] |
PRKCZ | Protein kinase C zeta type | Ser/Thr | nonreceptor | [60] |
MARK2 | MAP/microtubule affinity- | Ser/Thr | nonreceptor |
[61] |
Regulating kinase 2, Par-1 |
|
Phosphatases | | | |
PTPN1 | Tyrosine-protein phosphatase non | Tyr | nonreceptor | [19, 62–64] |
receptor type 1, PTP1B |
PTPN6 | Tyrosine-protein phosphatase non | Tyr | nonreceptor |
[65] |
receptor type 6, SHP1 |
PTPN11 | Tyrosine-protein phosphatase non- | Tyr | nonreceptor |
[66] |
receptor type 11, SHP2 |
PTPN12 | Tyrosine-protein phosphatase non- | Tyr | nonreceptor |
[67] |
receptor type 12, PTP-PEST |
PTPN14 | Tyrosine-protein phosphatase non- | Tyr | nonreceptor |
[68] |
receptor type 14, PEZ |
ACP1 | Acid phosphatase of erythrocyte, LMW-PTP | Tyr | nonreceptor | [69, 70] |
PTPRJ | Receptor-type tyrosine-protein | Tyr | Receptor |
[71] |
phosphatase eta (R-PTP-eta), DEP1 |
PTPRM | Receptor-type tyrosine-protein | Tyr | Receptor | [72–74] |
phosphatase mu (RPTP mu) |
PTPRT | Receptor-type tyrosine-protein | Tyr | Receptor |
[75] |
phosphatase T (R-PTP-T) |
PTPRU | Receptor-type tyrosine-protein | Tyr | Receptor | [76, 77] |
phosphatase U (R-PTP-U) |
PTPRK | Receptor-type tyrosine-protein | Tyr | Receptor | [78, 79] |
phosphatase kappa |
PTPRF | Receptor-type tyrosine-protein | Tyr | Receptor | [80–82] |
phosphatase F, LAR |
PPP2CA | Serine/threonine-protein phosphatase 2A | Ser/Thr | nonreceptor | [83–85] |
catalytic subunit alpha isoform |
|