Development and Validation of HPTLC Method for Estimation of Safinamide Mesylate in Bulk and in Tablet Dosage Form

<table class="table-group" id="tab4"><tr><td><table class="table"><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr class="thead"><td align="left">Parameters</td><td align="center">% R.S.D.*</td></tr><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr><td align="left">Mobile phase composition</td><td align="center">0.90</td></tr><tr><td align="left">Mobile phase volume</td><td align="center">0.81</td></tr><tr><td align="left">Development distance</td><td align="center">0.65</td></tr><tr><td align="left">Activation of TLC plate</td><td align="center">0.81</td></tr><tr><td align="left">Duration of saturation</td><td align="center">0.70</td></tr><tr><td align="left">Time from spotting to chromatography</td><td align="center">0.50</td></tr><tr><td align="left">Time from chromatography to scanning</td><td align="center">0.43</td></tr><tr class="table-tr"><td colspan="2"><hr class="tbody-hr"/></td></tr></table></td></tr><tr class="table-fn"><td>
                  *Mean of three estimations at each level.<br/></td></tr></table>

International Scholarly Research Notices

tab4

Table 4

Table 4: Development and Validation of HPTLC Method for Estimation of Safinamide Mesylate in Bulk and in Tablet Dosage Form 