International Journal of Family Medicine

Research Article

Chronic Condition Clusters and Polypharmacy among Adults

Table 3

Weighted percentage with polypharmacy. Unadjusted and adjusted odds ratio and 95% confidence intervals for chronic condition clusters. From logistic regressions on polypharmacy. Medical Expenditure Panel Survey, 2009.


	Weighted percentage with polypharmacy	Estimates from logistic regressions on polypharmacy
	Percentage	OR	95% CI	Sig.	AOR	95% CI	Sig.

CM	18.3	0.13	(0.10, 0.15)	^***	0.23	(0.18, 0.30)	^***
Resp.	7.2	0.04	(0.03, 0.07)	^***	0.15	(0.09, 0.24)	^***
Musc.	7.9	0.05	(0.04, 0.06)	^***	0.09	(0.06, 0.13)	^***
CM and Musc.	41.2	0.39	(0.32, 0.48)	^***	0.45	(0.35, 0.57)	^***
CM and Resp.	41.8	0.40	(0.30, 0.55)	^***	0.53	(0.38, 0.75)	^***
Musc. and Resp.	28.3	0.22	(0.15, 0.32)	^***	0.32	(0.21, 0.48)	^***
CM, Resp. and Musc.	64.1	(Reference group)

CM	18.3	(Reference group)
Musc.	7.9	0.38	(0.31, 0.48)	^***	0.38	(0.30, 0.49)	^***
Resp.	7.2	0.35	(0.24, 0.52)	^***	0.62	(0.40, 0.96)	^*

Musc.	7.9	(Reference group)
Resp.	7.2	0.91	(0.59, 1.39)		1.62	(1.01, 2.60)	^*

CM and Musc..	41.2	(Reference group)
CM and Resp	41.8	1.03	(0.80, 1.32)		1.19	(0.92, 1.54)

Musc. and Resp.	28.3	(Reference group)
CM and Musc.	41.2	1.77	(1.29, 2.42)	^***	1.42	(1.00, 2.01)
CM and Resp.	41.8	1.82	(1.25, 2.65)	^**	1.68	(1.11, 2.56)	^*

Note: Based on 10,528 adults alive at the end of 2009, reported having at least one chronic condition (cardio-metabolic, musculoskeletal, or respiratory condition). All analyses accounted for complex survey design of the Medical Expenditure Panel Survey. The regressions also include intercept terms and parameter estimates for other variables controlled are not presented. Asterisks represent statistically significant group differences compared to the reference group. “0 to 5 drugs” is the reference group for the dependent variable. CM: cardio-metabolic; Musc.: musculoskeletal; Resp.: respiratory; Wt: weighted; OR: Odds ratio; AOR: adjusted Odds ratio; CI: confidence interval.
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