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| Chemical | Trade name | Use | Application | RAS usage | Licensing | Possible worker hazards |
|
| Iodophore | Fam30 (Evans Vanadine) | GD | Footbaths, disinfecting equipments, nets | Common | NMA | Irritation to eyes, skin, upper respiratory tract, and mucous membranes. Fatal if ingested (MSDS) |
| Potassium peroxomonosulphate, Sulphamic acid, Sodium alkyl benzene sulphonate | Virkon | GD | As above | Common | NMA | Can cause serious eye damage. Powder is irritating to skin and to mucus membranes |
| Sodium hypochlorite | | GD | Disinfecting equipment | Common | | Corrosive, causes burns to skin and eyes. Harmful by ingestion, inhalation and through skin contact. Skin irritant (MSDS) |
| Formaldehyde | Formalin | Ectoparasites, antifungus, pathology | Bath or flow through treatment | Occasional | NMA | Irritant to skin, eyes, nose, and carcinogen (1) |
| Iodine | | Antibacterial/ fungus for eggs | Bath treatment | Occasional | NMA | Irritant to eyes, skin, nose, and neurological and cardiovascular effects effects (1) |
| Sodium chloride | Table salt | Ectoparasites, NH4 and NO3 toxicity management | Bath or permanent prophylaxis around 5 ppt | Common | NMA | |
| Benzalkonium chloride | Benzalkonium chloride | Gill parasites | Bath treatment | Possible | NMA | Very hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation. Hazardous in case of skin contact (corrosive), of eye contact (corrosive) Mutagen, and of reproductive health hazard (MSDS) |
| Chloramine T | Gill parasites | Bath treatment | Possible | NMA | Irritant of mucous membranes and upper respiratory tract., may produce pulmonary sensitization or allergic asthma (MSDS) |
| Potassium permanganate | | Ectoparasites | Bath treatment | Possible | NMA | Harmful if swallowed. Irritant. Readily absorbed through skin (MSDS). |
| | Ectoparasites | Bath treatment | Possible | NMA | May cause eye irritation; may be harmful if absorbed through the skin and cause skin irritation. Irritant to respiratory Tract (MSDS) |
| (MSDS)Ozone (O3) | NA | GD, oxidation of suspended organic solids | Side stream loop | Occasional | NMA | Irritant to eyes and lungs, chronic respiratory diseases (1) |
| Hydrogen peroxide (H2O2) | | Disinfection, Ectoparasites Supplementary oxygenation | Bath treatment Continuous dosing | Less common | NMA (MA sea lice treatment only) | Irritant to eyes, nose, and throat (1) |
| Bronopol | Pyceze | Fungicide | Bath treatment (eggs and juveniles) | Common | MA? | Harmful in contact with skin and if swallowed. Irritating to respiratory system and skin. Risk of serious damage to eyes (MSDS) |
| Sodium hydroxide/caustic soda (NaOH) | | pH buffer (high solubility—strong alkali), disinfectant | Episodic or continuous dosing | Common | NMA | Irritant to eyes, skin, throat; respiratory system (1) |
| Sodium carbonate/soda ash (Na2CO3) | | pH buffer (high solubility) | Episodic or continuous dosing | Common | NMA | Hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation (lung irritant) Skin sensitiser (MSDS) |
| Sodium bicarbonate/baking soda (NaHCO3) | | pH buffer (high solubility) | Episodic or continuous dosing | Common | NMA | |
| Calcium carbonate/calcite, inc. crushed shell (CaCO3) | | pH buffer (moderate solubility) | Continuous dosing | Occasional | NMA | Irritant to eyes, skin, throat; respiratory system effects (1) |
| Slaked lime | | pH buffer (moderate solubility) | Continuous dosing | Occasional | NMA | Irritant and respiratory hazard (1) |
| Calcium hydroxide/hydrated lime (Ca(OH)2) | | pH buffer (moderate solubility) | Continuous dosing | Occasional | NMA | Irritant eyes, skin, throat; respiratory system (1) |
| Dolomite (CaMg(CO3)2) | | pH buffer (low solubility) | Continuous dosing | Common in less intensive systems | NMA | Respiratory and eye irritant (MSDS) |
| Monosodium phosphate (NaH2PO4) | | pH buffer (high solubility—weak acid) | Episodic dosing | Occasional that is in concrete tank systems | NMA | Skin, eye and respiratory irritant (MSDS) |
| 2-Phenoxyethanol | | Anaesthetic | Bath treatment | Common | MA? | |
| Tricaine methanosulfonate | MS22 | Anaesthetic | Bath treatment | Common | MA? | |
| Methanol (CH3OH) | | Solvent for example, anaesthetics | Bath treatment | Common | NMA | Irritant eyes, skin, respiratory system, neurological effects (1) |
| Amoxycillin | | Antibiotic | In feed | Rarely | MA | May cause sensitization by skin contact, or lead to allergic reaction. This material is believed to show cross-allergenicity with penicillin (MSDS) |
| Oxylinic acid | | Antibiotic | In feed | Rarely | MA | Hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation. Also a mutagen (MSDS) |
| Floxacillin | | Antibiotic | In feed | Rarely | MA | |
| Oxytetracycline hypochloride/dihydrate | | Antibiotic | In feed | Rarely | MA | Eye, skin, and respiratory irritant; reproductive and fetal effects (MSDS) |
| Florfenicol | | Antibiotic | In feed | Rarely | MA | Smith (2008). Links to human resistance and aquaculture have been raised and challenged. Florfenicol may cause allergic reactions in susceptible individuals. Based on animal studies, florfenicol may cause slight eye irritation, constipation, changes in blood cell counts, changes in stool, or liver effects. It may also cause developmental effects or effects to male reproductive organs (MSDS). |
| Erythromycin | | Antibiotic | In feed | Rarely | MA | Eye and skin irritant; hazardous by ingestion; the substance is toxic to blood, kidneys, lungs, liver, and mucous membranes. Repeated or prolonged exposure to the substance can produce target organs damage (MSDS) |
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