(a) The left panels show angiograms of a stable angina patient who underwent successful stent implantation in the native left anterior descending coronary artery with SES and the first diagonal branch with BMS. More than 11 months after stenting, severe thrombotic occlusion occurred at the proximal SES site, 1 week after cessation of antiplatelet medication. Despite complete revascularization by thrombus aspiration, the patient died of multiorgan failure 1 week later. (b) Macroscopically, neointimal coverage of the SES struts was scarcely visible (*blood clot formed at agonal stage). In contrast, complete coverage by neointima was observed at the BMS site. (c) Microscopic observation demonstrated no obvious endothelialized struts at the SES site, even at the portion where a mild proliferative response of smooth muscle cells was evident. At the luminal surface of these nonendothelialized struts, the remnants of fibrin-rich thrombus were visible. (d) In the BMS segment, however, relatively large neointimal coverage of stent struts was observed. Furthermore, complete re-endothelialization was clearly visible.