Assessment of Some Inflammatory Biomarkers as Predictors of Outcome of Acute Respiratory Failure on Top of Chronic Obstructive Pulmonary Disease and Evaluation of the Role of Bacteria
Table 2
Comparison between different parameters among the responder and non-responder groups measured on admission.
Responders ( cases)
Nonresponders ( cases)
Significance ()
Age (yrs)
56.64 ± 8.18 (45–81)
56.5 ± 7.29 (45–65)
0.359 (0.719)
BMI (kg/m2)
27.7 ± 7.62 (16.6–44.1)
28 ± 9.2 (12.7–40.8)
0.231 (0.817)
Dyspnea (MMRC)
2.4 ± 0.87 (1–4)
3.4 ± 0.92 (2–4)
2.277 (0.023)
*
Current smoker (N (%))
8 (32%)
2 (25%)
= 1.0
Infection with Gram-negative, yes/no (%)
5/22 (22.7%)
4/7 (57%)
= 0.158
FEV1 percentage predicted
36.7 ± 17.1% (20.1–99.4)
35.1% (22.8–48.5)
1.638 (0.101)
Laboratory investigations
Total WBC (103/μL)
11.3 ± 7.5 (4.1–37.5)
13.4 ± 5.4 (7.44–21.51)
1.47 (0.141)
Na (mmol/L)
138.3 ± 3.7 (131–146)
134.8 ± 10.5 (114–151)
1.182 (0.237)
K (mmol/L)
4.4 ± 0.6 (3.5–5.8)
4.1 ± 0.6 (3.5–5.1)
0.822 (0.411)
BUN (mg/dL)
25.4 ± 15.9 (9–73)
34.1 ± 13.9 (13–54)
1.704 (0.088)
Cr (mg/dL)
0.9 ± 0.5 (0.4–3)
1.4 ± 0.7 (0.6–2.6)
1.904 (0.057)
Serum albumin (g/dL)
3.0 ± 0.5 (2.1–4)
2.7 ± 0.3 (2.4–3.2)
1.682 (0.093)
ABG
pH
7.31 ± 0.06 (7.21–7.45)
7.34 ± 0.08 (7.23–7.451)
0.742 (0.458)
PCO2 (mmHg)
67.2 ± 16 (38.6–106)
68.3 ± 27.8 (23.6–103)
0.653 (0.514)
PO2 (mmHg)
48. 8 ± 14.2 (25–80)
42.4 ± 4.4 (35.1–48)
1.088 (0.277)
Vital signs
HR
100 ± 11
103 ± 26
−0.167 (0.865)
SBP
141 ± 27
135 ± 22
−0.466 (0.641)
RR
29 ± 4
32 ± 7
−1.078 (0.281)
Yrs: years, MMRC: the Modified Medical Research Council, FEV1: forced expiratory volume in 1 second, WBC: white blood count, Na: sodium, K: potassium, BUN: blood urea nitrogen, Cr: creatinine, ABG: arterial blood gases, SBP: systolic blood pressure, RR: respiratory rate, HR: heart rate, pk/yr: pack/year, PaO2 (mmHg): partial arterial pressure of oxygen, PaCO2 (mmHg): partial arterial pressure of carbon dioxide, N: number of cases,*significant if P ≤ 0.05, = Fisher's exact test.
