International Scholarly Research Notices

Review Article

Prognostic Significance of Vascular Endothelial Growth Factor Serum Determination in Women with Ovarian Cancer

Table 1

Clinical and demographic characteristics of patients.


Author, year
		Tempfer et al., 1998 [21]	Gadducci et al., 1999 [22]	Chen et al., 1999 [23]	Oehler and Caffier, 2000 [24]	Cooper et al., 2002 [25]	Li et al., 2004 [26]	Harloziňska et al., 2004 [27]	Hefler et al., 2006 [28]	Mahner et al., 2010 [29]

Origin and Dates		1990–1995 Austria	1990–1997 Italy	1992–1998 Taiwan	Germany	1995–2000 Iowa	1999–2001 China	1997–2002 Poland	1990–2003 Austria, Iowa, Italy, Taiwan	1996–2004 Germany

Number of cases		60	53	56	41	101^$	50	86	314	37

Age, mean or median* (range), years		55.6* (36–71)	59* (23–81)	52.5* (21–88)	62 (32–83)	64 (20–78)	NA	NA	59.9	58.61* (26–78)

FlGO stage	I	7	19	14	5	20	17	14	56	1
	II	12	1	6	2	20	17	9	27	1
	III	27	22	32	30	81	33	37	177	29
	IV	14	11	4	4	81	33	26	46	6

Grade	G1	21	17	21	NA	39	13	19	60	0
	G2	39	12	35	NA	39	13	41	88	9
	G3	39	24	35	NA	61	30	26	150	27

Epithelial ovarian cancer	Serous	28	33	30	32	81	15	49	166	31
	Mucinous	23	6	4	2		9	4	41	0
	Undifferentiated	3	6	8	0		19	13	15	4
	Endometrioid	3	7	10	7		0	20	39	1
	Clear cell	2	0	4	0	0	0	0	9	1
	Others	1	1	0	0	0	0	0	44	0

Nonepithelial ovarian cancer		0	0	0	0	0	7	0	0	0

Ascites	>500 mL/presence**	NA	21**	NA	NA	67**	22	64**	NA	21
Ascites	<500 mL/absence**	NA	12**	NA	NA	34**	28	22**	NA	15

Residual disease	<2 or 1*** cm	38	9	40	11	68***	44	32	164***	22
Residual disease	>2 or 1*** cm	22	24	16	30	33***	6	54	64***	14

Lymph node involvement	yes	23	NA	NA	NA	NA	12	NA	38	10
Lymph node involvement	no	37	NA	NA	NA	NA	38	NA	63	11

^$: Cooper study contains a small group of peritoneal and fallopian tube malignant cancers; NA: not available data; *: Median values; **: Numbers of patients with presence/absence of ascites; ***: Numbers of patients with residual disease < or >1 cm.