Cathepsin D Expression in Colorectal Cancer: From Proteomic Discovery through Validation Using Western Blotting, Immunohistochemistry, and Tissue Microarrays
Figure 6
Adjacent sections of primary colorectal tumor stained for cathepsin D (a) (DAB substrate, brown). CD 68 staining (b) confirmed that very strong expression of cathepsin D in a population of cells within stromal tissue was associated with macrophage (DAB substrate, brown). Sections were counterstained with haematoxylin (blue) (40x objective).