Biological Markers and Response to Neoadjuvant Taxane-Based Chemotherapy in Patients with Locally Advanced Breast Cancer

<table class="table-group" id="tab6"><tr><td><table class="table"><tr><td class="thead-hr" colspan="7"><hr/></td></tr><tr class="thead"><td align="left">variable</td><td align="center">Her2/neu+ and inactive p53</td><td align="center">Her2/neu− and intact p53</td><td align="center">Her2/neu+ and intact p53</td><td align="center">Her2/neu− and inactive  p53</td><td align="center">Total</td><td align="center"><i>P</i> value</td></tr><tr><td class="thead-hr" colspan="7"><hr/></td></tr><tr><td align="left">HmR+</td><td align="center">0</td><td align="center">51</td><td align="center">3</td><td align="center">20</td><td align="center">74</td><td align="center" rowspan="2">&lt;0.0001</td></tr><tr><td align="left">HmR−</td><td align="center">9</td><td align="center">3</td><td align="center">8</td><td align="center">1</td><td align="center">21</td></tr><tr><td align="left" colspan="7"><hr/></td></tr><tr><td align="left">Total</td><td align="center">9</td><td align="center">54</td><td align="center">11</td><td align="center">21</td><td align="center">95</td><td align="center"> </td></tr><tr class="table-tr"><td colspan="7"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

Coexpression of Her2/neu and p53 according to HmR status.

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Table 6

Table 6: Biological Markers and Response to Neoadjuvant Taxane-Based Chemotherapy in Patients with Locally Advanced Breast Cancer 