Clinical Study

Novel m.15434C > A (p.230L > I) Mitochondrial Cytb Gene Missense Mutation Associated with Dilated Cardiomyopathy

Figure 1

DGGE investigations illustrating the detection of heteroplasmic and homoplasmic sequence variations of the mitochondrial cytochrome b gene. The arrow shows destabilizing sequence variations in a heteroplasmic state in the index patient (P5) who presented with dCMP (H: homoduplexes, h: heteroduplex) and homoplasmic patterns in the other patients with dCMP (P1 to P4 and P6 to 23).
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