The Importance of Myeloperoxidase in Apocynin-Mediated NADPH Oxidase Inhibition
Figure 1
MPO activity (a) and the effect of apocynin (1.0 mM for 2 hours) on ROS production (b) by PBMC, DMSO-differentiated HL-60 cells, IFN-γ/TNF-α-differentiated HL-60 cells, and PMN. Percentage of inhibition was calculated in comparison to the cells incubated with the vehicle (DMSO). Data represents at least four separated experiments (*, **, ***, Mann-Whitney test).