Research Article

The Importance of Myeloperoxidase in Apocynin-Mediated NADPH Oxidase Inhibition

Figure 1

MPO activity (a) and the effect of apocynin (1.0 mM for 2 hours) on ROS production (b) by PBMC, DMSO-differentiated HL-60 cells, IFN-γ/TNF-α-differentiated HL-60 cells, and PMN. Percentage of inhibition was calculated in comparison to the cells incubated with the vehicle (DMSO). Data represents at least four separated experiments (* 𝑃 < 0 . 0 5 , ** 𝑃 > 0 . 0 1 , *** 𝑃 < 0 . 0 0 5 , Mann-Whitney test).
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(a)
260453.fig.001b
(b)