N-Aryl Lactams by Regioselective Ozonation of N-Aryl Cyclic Amines
Figure 3
Plausible rearrangement mechanisms of aryl-morpholinyl hydrotrioxide intermediate formed by ozonation of 4-(4-nitrophenyl)morpholine (3). Pathway A leads to the formation of the corresponding lactame (4), pathway B to dehydro (6), diformyl (7), and dimeric (8) derivates.