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Authors | Study design | Device | Injected activity | Time between tracer injection and image acquisition (min) | PET acquisition protocol | Image analysis | Reference standard | Sensitivity of FDG-PET or PET/CT* | Specificity of FDG-PET or PET/CT* |
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Treglia et al. [5] | Retrospective multicenter | PET/CT | 259–407 MBq | 60 | Static acquisition | Qualitative | Histology and/or clinical/imaging followup | 17% | NC |
Kauhanen et al. [6] | Prospective multicenter | PET/CT | 377 MBq | 60 | Static acquisition (3 min per bed position) | Qualitative and semiquantitative | Histology and/or clinical/imaging followup | 53% | NC |
Ozkan et al. [7] | Retrospective single center | PET/CT | 296–370 MBq | 60 | Static acquisition (4 min per bed position) | Qualitative and semiquantitative | Histology and/or clinical/imaging followup | 93% | 68% |
Gómez-Camarero et al. [8] | Retrospective single center | PET and PET/CT | 333–434 MBq | 60 | Static acquisition | Qualitative and semiquantitative | Histology and/or clinical/imaging followup | 88% | 85% |
Jang et al. [10] | Prospective single center | PET/CT | 370 MBq | 60 | Static acquisition (4 min per bed position) | Qualitative | Histology and/or clinical/imaging followup | 63% | NC |
Skoura et al. [12] | Retrospective single center | PET/CT | 370 MBq | 60 | Static acquisition (4 min per bed position) | Qualitative and semiquantitative | Histology and/or clinical/imaging followup | 47% | NC |
Marzola et al. [13] | NR; multicenter | PET/CT | 2.2 MBq/kg | 60 | Static acquisition (3 min per bed position) | Qualitative and semiquantitative | Histology | 61% | NC |
Bogsrud et al. [14] | Retrospective single center | PET and PET/CT | 740 MBq | 60–75 | Static acquisition (5 min per bed position) | Qualitative | Histology and/or clinical/imaging followup | 45% | 93% |
Conry et al. [15] | Retrospective multicenter | PET/CT | 195–550 MBq | 50–75 | Static acquisition (1.5/5 min per bed position) | Qualitative and semiquantitative | Histology and/or clinical/imaging followup | 78% | NC |
Beheshti et al. [16] | Prospective single center | PET/CT | 370 MBq | 60 | Static acquisition (4 min per bed position) | Qualitative and semiquantitative | Histology and/or clinical/imaging followup | 58% | NC |
Faggiano et al. [17] | Retrospective multicenter | PET | 222–370 MBq | 60–90 | Static acquisition (4 min per bed position) | Qualitative | Histology and/or clinical/imaging followup | 50% | NC |
Koopmans et al. [18] | Prospective single center | PET | NR | NR | Static acquisition(5 min per bed position) | Qualitative | Histology and/or clinical/imaging followup | 24% | NC |
Rubello et al. [19] | Prospective multicenter | PET/CT | 5.5 MBq/kg | 60–90 | Static acquisition (4 min per bed position) | Qualitative and semiquantitative | Histology | 79% | 100% |
Oudoux et al. [20] | Prospective multicenter | PET/CT | 310–450 MBq | 60 | Static acquisition | Qualitative and semiquantitative | Histology and/or clinical/imaging followup | 76% | NC |
Giraudet et al. [21] | Prospective single center | PET/CT | 5 MBq/Kg | 60 | Static acquisition | Qualitative and semiquantitative | Histology and/or clinical/imaging followup | 32% | NC |
Czepczyński et al. [22] | NR; single center | PET | NR | NR | Static acquisition | Qualitative | Histology and/or clinical/imaging followup | 58% | NC |
Beuthien-Baumann et al. [23] | Retrospective single center | PET | 370 MBq | 60 | Static acquisition | Qualitative | Histology and/or clinical/imaging followup | 47% | NC |
Ong et al. [24] | Retrospective single center | PET and PET/CT | 555 MBq | Minimum 45 | Static acquisition (4 min per bed position) | Qualitative and semiquantitative | Histology and/or clinical/imaging followup | 62% | NC |
Iagaru et al. [25] | Retrospective single center | PET and PET/CT | 550 MBq | 45/60 | Static acquisition (4/5 min per bed position) | Qualitative | Histology and/or clinical/imaging followup | 86% | 83% |
Gotthardt et al. [26] | NR; multicenter | PET | 350 MBq | 60 | Static acquisition | Qualitative | Histology and/or clinical/imaging followup | 70% | NC |
De Groot et al. [27] | Prospective single center | PET | 400 MBq | 90 | Static acquisition (5 min per bed position) | Qualitative | Histology and/or clinical/imaging followup | 41% | NC |
Szakáll et al. [28] | Retrospective single center | PET | 5.55 MBq/Kg | 40 | Static acquisition (10 min per bed position) | Qualitative | Histology and/or clinical/imaging followup | 95% | NC |
Diehl et al. [29] | Retrospective multicenter | PET | 300–500 MBq | Minimum 30 | Static acquisition | Qualitative | Histology and/or clinical/imaging followup | 78% | 79% |
Hoegerle et al. [30] | Prospective single center | PET | 330 MBq | 90 | Static acquisition | Qualitative | Histology and/or clinical/imaging followup | 60% | 100% |
Brandt-Mainz et al. [31] | Prospective single center | PET | 350 MBq | 30 | Static acquisition (15–20 min per bed position) | Qualitative | Histology and/or clinical/imaging followup | 76% | NC |
Adams et al. [32] | Prospective single center | PET | 374 MBq | 60 | Static acquisition (12–15 min per bed position) | Qualitative | Histology and/or clinical/imaging followup | 87% | NC |
Musholt et al. [33] | NR; single center | PET | 370–555 MBq | 40 | Static acquisition (10 min per bed position) | Qualitative | Histology and/or clinical/imaging followup | 90% | NC |
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