Angiotensin Type 1a Receptor Signaling Is Not Necessary for the Production of Reactive Oxygen Species in Polymorphonuclear Leukocytes
Figure 2
H2O2 production in PMNs. (a) Level of H2O2 in polymorphonuclear leukocytes (PMLs) from Ang II type 1a receptor knockout mice (AT1KO), C57BL/6 wild type mice (Control; ), and C57BL/6 wild type mice treated with losartan (ARB; ) after addition of S. aureus. **; compared to control mice (Control) at baseline. (b) H2O2 levels in polymorphonuclear leukocytes (PMLs) from Ang II type 1a receptor knockout mice (AT1KO; ), C57BL/6 wild type mice (Control; ), and C57BL/6 wild type mice treated with losartan (ARB; ) after phorbol myristate acetate (PMA) stimulation. **; compared to wild-type mice (Control) at baseline.