Review Article

Functional Mechanisms and Roles of Adaptor Proteins in Abl-Regulated Cytoskeletal Actin Dynamics

Table 1

Adaptor proteins for c-Abl in mice.

Adaptor proteinTarget domain in AblReferences

c-Crk : CrkI, CrkIIProline-rich motif[5557]
CrkLProline-rich motif [58]
Abi1/E3B1Proline-rich motif/SH3[5961]
Abi2/ArgBP1Proline-rich motif/SH3[62, 63]
CAP/Ponsin/SH3P12Proline-rich motif[64, 65]
VinexinProline-rich motif[66]
NckProline-rich motif[67]
CblProline-rich motif[68]
ArgBP2/Sorbs2Proline-rich motif[63]

Adaptor proteins that bind Abl and function in Abl-mediated signaling in mouse cells are listed together with the target domain in Abl.