Clinical Study
Serum Levels of Biochemical Markers of Traumatic Brain Injury
Table 2
Summary of overall ROC curve analyses, estimates, and associated 95% confidence intervals (95% CI’s).
| | TBI versus Control |
| | Marker | AUC | Optimal cutoff | Sensitivity at cutoff | Specificity at cutoff | | [95% C.I.] | [95% C.I.] | [95% C.I.] |
| | S-100β | 0.868 | 10 pg/mL | 77.8% | 93.3% | | [0.780, 0.930] | [62.9%, 88.8%] | [81.7%, 98.5%] | | NSE | 0.820 | 8.15 ng/mL | 71.1% | 82.2% | | [0.725, 0.893] | [55.7%, 83.6%] | [67.9%, 92.0%] | | MBP | 0.659 | 65 pg/mL | 71.1% | 55.6% | | [0.552, 0.756] | [55.7%, 83.6%] | [40.0%, 70.3%] |
|
|
