International Scholarly Research Notices

Research Article

Anti-Inflammatory, Analgesic, and Antipyretic Activities of the Ethanol Extract of Piper interruptum Opiz. and Piper chaba Linn.

Table 2

Effects of PI and PC extracts on body weight and thymus weight in cotton pellet-induced granuloma formation in rats.
DoseBody weight (g)Dry thymus weight
(mg/kg)InitialFinalGain(mg/100 g)
Control— 3 8 4 . 2 ± 2 0 . 5 3 9 2 . 5 ± 2 0 . 1 8 . 3 ± 2 . 5 2 2 . 2 ± 1 . 4
Prednisolone5 3 8 4 . 2 ± 2 0 . 9 3 6 7 . 5 ± 1 3 . 3 − 1 6 . 7 ± 1 0 . 8 ∗ 1 7 . 8 ± 0 . 7 ∗
Aspirin300 4 0 6 . 7 ± 1 5 . 7 3 9 9 . 2 ± 1 3 . 6 − 7 . 5 ± 2 . 8 2 0 . 0 ± 1 . 0
PI extract1,200 3 7 3 . 3 ± 9 . 4 3 5 6 . 7 ± 9 . 4 ∗ − 1 6 . 6 ± 6 . 7 ∗ 1 5 . 2 ± 0 . 7 ∗
PC extract1,200 3 8 4 . 2 ± 9 . 9 3 3 9 . 2 ± 1 3 . 5 ∗ − 4 5 . 0 ± 5 . 3 ∗ 1 2 . 6 ± 1 . 4 ∗
Data represent mean ± S.E.M. ( 𝑛 = 6 ). *Significantly different from the control group, 𝑃 < 0 . 0 5 .