PKCδ Regulates Translation Initiation through PKR and eIF2α in Response to Retinoic Acid in Acute Myeloid Leukemia Cells
Figure 10
eIF2α is involved in ATRA-mediated expression of c-myc, DAP5, TG2, and P70S6 in NB4 cells. NB4 cells were transfected with control or eIF2α siRNA for 48 h in the absence (a) or in the presence of ATRA (1 μM, 48 h) (b). (c) Densitometry analysis (lower panel) represents relative expression of Western blot bands after treatments with control or eIF2α siRNA in the presence of ATRA. Protein bands were normalized expression based actin levels.
