Elimination of the Actin-Binding Domain in Kelch-Like 1 Protein Induces T-Type Calcium Channel Modulation Only in the Presence of Action Potential Waveforms
Figure 7
The APW-like stimulus produces an effect similar to an actual APW. (a) Stimulus (APW-like) created to replicate an actual APW (top) and APW-like stimuli with AHP slopes of 0.70 mV/ms and 0.35 mV/ms were compared. (b) Percentage of increase in calcium influx obtained with the stimuli shown above with respect to control; the magnitude of the changes induced by the original APWs is shown with dotted lines (; ); .