Journal of Allergy

Research Article

L-Carnitine Improves the Asthma Control in Children with Moderate Persistent Asthma

Table 4

Correlation between free and total carnitine levels with C-ACT, FEV1% of predicted and FEV1/FVC ratio in asthmatic children at the beginning of the study.


Variable ()		r	95% CI

C-ACT 13.1 ± 1.43	Total S Carnitine 40.1±2.63	0.36	0.09, 0.58	<0.01*
C-ACT 13.1 ± 1.43	Free S Carnitine 30.3 ± 1.8	0.88	0.8, 0.9	<0.001*

FEV1 (% of predicted)	Total S Carnitine	0.95	0.91, 0.97	<0.001*
FEV1 (% of predicted)	Free S Carnitine	0.7	0.52, 0.82	<0.001*

FEV1/FVC Mean ± SD 60.2 ± 4.5	Total S Carnitine	0.26		>0.05
FEV1/FVC Mean ± SD 60.2 ± 4.5	Free S Carnitine	0.07		>0.05

C-ACT: Childhood-Asthma control test. FEV1/FVC: Forced Expiratory Volume in 1st second/Forced Vital Capacity Ratio. (*) is significant, r correlation coefficient, CI confidence interval.
The table showed the correlation between serum carnitine (free and total) and C-ACT and some pulmonary function parameters in asthmatic children at the beginning of the study. C-ACT and FEV₁ (% of predicted) had significant positive correlations with total and free serum carnitine. However, there were no significant correlations between FEV₁/FVC and the levels of total and free serum carnitine.