International Scholarly Research Notices

Research Article

Antimicrobial or Subantimicrobial Antibiotic Therapy as an Adjunct to the Nonsurgical Periodontal Treatment: A Meta-Analysis

Outcomes measured in systemic antibiotic treatment as an adjunctive therapy in scaling and root planing.


Clinical and microbiological outcomes	Caton et al. 2000 [10]	Golub et al. 2001 [7]	Novak et al. 2002 [11]	Preshaw et al. 2004 [12]	Preshaw et al. 2008 [18]	Guerrero et al. 2005 [14]	Reinhardt et al. 2007 [15]	Needleman et al. 2007 [16]	Griffiths et al. 2011 [17]

(1) CAL gain	*	*	*	*	*	*	*	*	*
(2) PD reduction	*	*	*	*	*	*	*	*	*
(3) % of BOP	*		*	*	*	*	*	*
(4) Adverse events				*		*
(5) Gingival inflammation index		*	*
(6) Plaque index									*
(7) Metabolic activity in GCF		*						*
(8) Proportion of spirochetes	*
(9) Antibiotic sensitivity of microflora		*

CAL: clinical attachment level; PD: probing depth; BOP: bleeding on probing depth; metabolic activity in GCF gingival crevicular fluid.