Research Article

Antimicrobial or Subantimicrobial Antibiotic Therapy as an Adjunct to the Nonsurgical Periodontal Treatment: A Meta-Analysis

Table 7

Forest plot (meta-analysis, random effect model) indicating the cumulative effect sizes for percentage of sites with clinical attachment level gain at sites with severe periodontitis (≥7 mm).

Percentage of sites with CAL gain at sites with severe periodontitis (≥7 mm) Std diff in means and 95% CI
StudyAntibioticPlaceboStd diff in means
95% Cl
Z value value

Caton et al., 2000 [10]90930.2441.6470.1581207.tab.004
Preshaw et al., 2004 [12]10100.1781.2830.199
Novak et al., 2002 [11]1071020.7751.6720.094
Mohammad et al., 2005 [8]66760.5303.0960.002
Guerrero et al., 2005 [14]2021−0.615−1.9250.054
Needleman et al., 2007 [16]16180.2000.5820.561
Synthesis3093200.2443.0350.002

CAL: clinical attachment level, , confidence level 95%.