Research Article
Studies on Paliperidone in OROS Tablets: Extraction Procedure and Chromatographic Analysis
Figure 4
LC chromatograms of paliperidone sample solution, placebo and degraded samples. (A) paliperidone sample solution (30 μg mL−1); (B) placebo solution; (C) paliperidone sample solution after basic degradation (NaOH 0,1 N, 1 h); (D) acid degradation (HCl 0,1 N, 1 h); (E) oxidative degradation (H2O2 30%, 6 h); (F) photodegradation (UV chamber, 60 min); (G) thermal degradation (60°C, 96 h).
