Research Article
Studies on Paliperidone in OROS Tablets: Extraction Procedure and Chromatographic Analysis
Table 6
Results from stability of analytical solutions applied to LC analysis of paliperidone in extended-release OROS tablets.
| | Amount of paliperidonea (%) | | Time (h) | 4°C | 25°C | 40°C | | Standard solution | Sample solution | Standard solution | Sample solution | Standard solution | Sample solution |
| | 0 | 100.11 | 99.97 | 100.45 | 100.07 | 101.12 | 100.34 | | 24 | 100.05 | 99.88 | 99.50 | 99.44 | 99.94 | 99.74 | | 48 | 101.09 | 99.80 | 100.78 | 98.94 | 100.87 | 99.03 | | 72 | 99.15 | 99.71 | 98.92 | 98.51 | 100.95 | 99.11 |
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aMean of three amounts, assayed in triplicate. Solutions stored at 30.0 μg mL−1.
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