Clinical Study
Emotion Processing in Women with Schizophrenia Is Menstrual Cycle Phase and Affective Valence Dependent: An fMRI Study
Table 4
Cerebral activations during processing of negative emotions in control and schizophrenia women during the follicular phase.
| Anatomical area | L/R | Control women | Schizophrenia women | BA | MNI coordinates | Z-score | Voxels | BA | MNI coordinates | Z-score | Voxels | | x | y | z | | | | x | y | z | | |
| Fusiform | R | 20 | 42 | −35 | −21 | 4.73 | 4196 | 19 | 35 | −70 | −18 | 5.95 | 3834 | | L | 19 | −28 | −70 | −14 | 4.55 |
*
| 19 | −24 | −80 | −18 | 5.73 |
*
| Calcarine | R | | | | | | | 18 | 4 | −88 | −10 | 6.17 |
*
| Middle occipital | R | 18 | 35 | −91 | −18 | 6.07 |
*
| 19 | 32 | −91 | 10 | 5.26 |
*
| | L | 18 | −35 | −88 | 10 | 5.41 |
*
| 19 | −35 | −80 | 4 | 4.76 |
*
| Inferior occipital | L | 37 | −46 | −70 | −4 | 6.25 |
*
| | | | | | | | R | | | | | | | 19 | 46 | −80 | −7 | 4.97 |
*
| Superior occipital | R | 17 | 21 | −88 | 7 | 4.86 |
*
| 18 | 24 | −91 | 18 | 5.35 |
*
| Inferior temporal | R | 37 | 42 | −52 | −7 | 5.46 |
*
| | | | | | | Hippocampus | L | — | −28 | −24 | −10 | 3.51 | 81 | | | | | | | Anterior temporal pole | L | 38 | −35 | 24 | −24 | 3.47 | 6 | | | | | | | Cerebellum | L | — | −10 | −74 | −21 | 4.45 | 4196 | — | −38 | −52 | −28 | 5.63 |
*
| | R | — | 32 | −56 | −28 | 4.91 |
*
| | | | | | | Thalamus | R | | | | | | | — | 10 | −24 | −4 | 3.60 | 37 | Superior parietal | L | 7 | −24 | −63 | 52 | 3.50 | 13 | | | | | | | Inferior parietal | | | | | | | | 40 | −38 | −38 | 46 | 3.40 | 11 | Precentral | R | 9 | 52 | 4 | 38 | 3.20 | 5 | 9 | 49 | 4 | 38 | 3.19 | 37 | | L | 6 | −28 | −10 | 56 | 3.48 | 19 | | | | | | | Middle frontal | R | 6 | 38 | 0 | 52 | 3.26 | 6 | | | | | | | Superior frontal | R | 6 | 24 | −10 | 74 | 3.78 | 18 | | | | | | | Inferior OFC | L | 11 | −35 | 38 | −18 | 3.72 | 7 | | | | | | | Inferior frontal | | | | | | | | 9 | 52 | 10 | 28 | 3.60 | 37 | SMA | L | 6 | −4 | 4 | 52 | 3.79 | 22 | 6 | 0 | 7 | 56 | 3.16 | 5 |
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L: left; R: right; BA: Brodmann area; SMA: supplementary motor area; OFC: orbitofrontal cortex; P uncorrected ≤0.001.
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