Analgesic and Toxicity Studies of Aminoacetylenic Isoindoline-1,3-dione Derivatives
Figure 3
Percent of increase in latency periods of mice treated with normal saline (negative control), aspirin (positive control), ZM4, and ZM5. Treated mice were challenged on a hot plate every 15 min for 1 hour after oral treatment. Values are expressed as mean ± S.E.M (). , and against normal saline and ZM4 and ZM5 against aspirin.
