Review Article

Intracoronary Imaging and Histopathology of Late Phase In-Stent Restenosis after Coronary Stent Implantation

Figure 11

Materials retrieved on the Filtrap. After the procedure, the net of the Filtrap was cut and fixed in formalin. The main samples captured on the net were stained with hematoxylin-eosin staining, special staining, and immunohistological staining. (a) Microscopic findings of main retrieved samples. (b) Hematoxylin-eosin stain: . The retrieved samples consisted of hypocellular deposits and were mainly composed of fibrin deposits with a few inflammatory cells (neutrophils). (c) Phosphotungstic acid hematoxylin staining (PTAH): . Fibrin deposits were confirmed by PTAH staining as blue. (d) Masson trichrome staining: . Fibrin deposits were also confirmed by this special staining as red. (e) Alcian blue staining: . Proteoglycans were only slightly detected. (f) Immunoreactivity to SMC α actin: . Smooth muscle cells were not detected in this material. (From JC Cases 5:e83-e86, 2012 with permission).
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