Clinical Study

Impact of Dual Antiplatelet Therapy with Proton Pump Inhibitors on the Outcome of Patients with Acute Coronary Syndrome Undergoing Drug-Eluting Stent Implantation

Table 1

Population characteristics.

Total ( š‘› = 1 7 6 )PPI group ( š‘› = 1 2 1 )Anti-H2 group ( š‘› = 5 5 ) š‘ƒ value < 0.05

Demographics characteristics
ā€ƒAge 6 4 . 3 1 Ā± 1 0 . 0 8 6 3 . 6 6 Ā± 1 0 . 5 6 6 5 . 7 5 Ā± 8 . 8 5 0.203
ā€ƒMale š‘› (%)145 (82.38)97 (80.16)48 (87.27)0.196
Clinical characteristics š‘› (%)
ā€ƒSmoke61 (34.65)45 (37.19)15 (27.27)0.265
ā€ƒDyslipidemia97 (55.11)65 (53.71)32 (58.18)0.697
ā€ƒFamiliar history63 (35.79)42 (34.71)21 (38.18)0.782
ā€ƒHypertension130 (73.86)85 (70.24)45 (81.81)0.152
ā€ƒObesity ( B M I > 3 0 Kg/m2)22 (12.50)11 (9.09)11 (20)0.074
ā€ƒDiabetes78 (44.31)50 (41.32)33 (49.09)0.43
ā€ƒPrevious CABG11 (6.25)11 (9.09)0 (0)0.048
ā€ƒPrevious AF5 (2.84)1 (0.82)4 (7.27)0.057
ā€ƒPrevious AMI28 (15.90)20 (16.52)8 (14.54)0.912
ā€ƒPrevious PCI38 (21.59)29 (23.96)9 (16.36)0.348
ā€ƒPrevious HF4 (2.27)3 (2.47)1 (1.81)0.784
ā€ƒRenal failure38 (21.59)28 (23.14)10 (18.18)0.587
ā€ƒAnemia š‘› (%)62 (35.22)50 (41.32)12 (21.81)0.019
Therapy at discharge š‘› (%)
ā€ƒACE inhibitors106 (60.22)75 (61.98)30 (54.54)0.443
ā€ƒ š›½ -blockers137 (77.84)94 (77.68)43 (78.18)0.903
ā€ƒStatine163 (92.61)109 (90.08)54 (98.18)0.111
Angiographics data
ā€ƒMultivessel disease š‘› (%)64 (36.36)44 (36.36)20 (36.36)0.865
ā€ƒNo. of stents1.26 Ā± 0.561.24 Ā± 0.601.25 Ā± 0.550.916

CABG: coronary artery bypass graft surgery; AF: atrial fibrillation; HF: heart failure; AMI: acute myocardial infarction; PCI: percutaneous coronary intervention.