Research Article
Comparison of Whole Genome Amplification Methods for Analysis of DNA Extracted from Microdissected Early Breast Lesions in Formalin-Fixed Paraffin-Embedded Tissue
Table 2
Assessment of fidelity of WGA of DNA extracted from breast cancer FFPE tissue. Amplification was performed by two methods: DOP and SCOMP. aCGH profiles of pre- (control) and post-amplification DNA samples were compared by correlation of raw aCGH data, segmentation and peaks of genomic alterations (means of three independent experiments).
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Third column (*) represents the extended set of 6 SCOMP amplified samples. values in brackets are calculated for difference with control repeats by two-tailed exact Mann-Whitney test; N/S: not significant. |