Application of a Reliable LC-MS/MS Method for Determination of Rizatriptan in Healthy Subject Samples: Demonstration of Assay Reproducibility by Incurred Sample Reanalysis
Figure 4
Mean plasma concentration-time profile of rizatriptan after oral administration of test (10 mg rizatriptan orally disintegrating tablets of a generic company) and a reference (MAXALT-MLT, 10 mg rizatriptan benzoate orally disintegrating tablets from Merck & Co. Inc, Whitehouse station, NJ 08889, USA) formulation to 40 and 32 healthy subjects under fasting and fed conditions, respectively.