Ulcers

Research Article

Stratification of Highest-Risk Patients with Chronic Skin Ulcers in a Stanford Retrospective Cohort Includes Diabetes, Need for Systemic Antibiotics, and Albumin Levels

Table 5

Adjusted and unadjusted odds of having a poor wound-healing outcome¹ ().


Predictors	Unadjusted		Adjusted
Predictors	OR²	95% CI³	OR²	95% CI³

Diabetes mellitus	6.38*	2.89–14.1	5.87*	1.36–25.3
Peripheral neuropathy	4.17*	1.99–8.76	0.97	0.24–3.91
Renal insufficiency	2.54*	1.26–5.15	1.32	0.42–4.1
Need for systemic antibiotics⁴	3.62*	1.65–7.95	3.88*	1.06–14.2
Peripheral arterial disease	2.31*	1.13–4.72	1.43	0.45–4.52
Albumin (per unit)	0.21*	0.09–0.48	0.20*	0.07–0.60
Hemoglobin (per unit)	0.79	0.65–0.95	1.05	0.73–1.4

¹Poor wound-healing outcome was defined as wounds that required amputation or did not heal after 1 year of followup. ²OR refers to odds ratio. ³95% CI refers to 95% confidence interval. ⁴All cases of systemic antibiotic administration were reviewed and found to reflect secondary infection of skin wound with the exception of 2 cases which were excluded from this analysis.
*indicates statistical significance at .