International Scholarly Research Notices

Research Article

[Retracted] Interaction of TMPyP4, TMPyP3, and TMPyP2 with Intramolecular G-Quadruplex Formed by Promoter Region of Bcl2 and KRAS NHPPE

Table 2

UV-Vis Absorption titration parameters for TMPyP4, TMPyP3, and TMPyP2 with four different Bcl2 and KRAS NHPPE-G-quadruplex DNA.
S. no.Name of G-quadrupelx DNA and cationic porphyrinSoret band shift (nm)Isobestic point (nm)Percentage hypochromicity
139Bcl2-TMPyP4423–441436.568.4%
239Bcl2-TMPyP3417–431427.055.0%
339Bcl2-TMPyP2No shift422.032.5%
4KRAS NHPPE-TMPyP4423–441435.559.7%
5KRAS NHPPE-TMPyP3417–431426.541.5%
6KRAS NHPPE-TMPyP2No shift422.023.0%
Soret band hypochromicity is calculated using the fomula: % Hypochromicity = [ ( € f r e e − € b o u n d ) / € f r e e ] × 1 0 0 .   € f r e e and € b o u n d are the extinction coefficient of free and bound porphyrin, respectively.