Research Article

[Retracted] Interaction of TMPyP4, TMPyP3, and TMPyP2 with Intramolecular G-Quadruplex Formed by Promoter Region of Bcl2 and KRAS NHPPE

Table 3

Data obtained from Job plot of Bcl2 and KRAS NHPPE G-quadruplex DNA with TMPyP4, TMPyP3, and TMPyP2 porphyrin drug.

S. no.Name of G-quadrupelx DNA and porphyrinValue of mole fraction of porphyrin matching with point of intersectionStoichiometry between G-quadruplex DNA and porphyrin

139Bcl2-TMPyP40.801 : 4.00
239Bcl2-TMPyP30.681 : 2.10
339Bcl2-TMPyP20.621 : 1.63
4KRAS NHPPE-TMPyP40.781 : 3.54
5KRAS NHPPE-TMPyP30.681 : 2.10
6KRAS NHPPE-TMPyP20.581 : 1.38