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Research Article

[Retracted] Interaction of TMPyP4, TMPyP3, and TMPyP2 with Intramolecular G-Quadruplex Formed by Promoter Region of Bcl2 and KRAS NHPPE

Table 6

ESI-MS experimental details indicating the presence of different populations of 39Bcl2 and KRAS quadruplex species after interaction with TMPyP4 at saturation molar ratio.
S. no.Interacting quadruplexInteracting ligandRatio of quadruplex : ligandComposition and charge of the complexDesignated mass of the peakRelative abundance of each peak
(1)39Bcl2TMPyP41 : 0 [ 𝑄 + 4 𝐾 ] 1 0 βˆ’ 125999
(2)39Bcl2TMPyP41 : 1 [ 𝑄 + 4 𝐾 + 1 𝑃 4 ] 1 0 βˆ’ 139618
(3)39Bcl2TMPyP41 : 2 [ 𝑄 + 4 𝐾 + 2 𝑃 4 ] 1 0 βˆ’ 153320
(4)39Bcl2TMPyP41 : 3 [ 𝑄 + 4 𝐾 + 3 𝑃 4 ] 1 0 βˆ’ 166815
(5)39Bcl2TMPyP41 : 4 [ 𝑄 + 4 𝐾 + 4 𝑃 4 ] 1 0 βˆ’ 180514
(6)KRASTMPyP41 : 0 [ 𝑄 + 4 𝐾 βˆ’ 1 0 𝐻 ] βˆ’ 1 6 59982
(7)KRASTMPyP41 : 1 [ 𝑄 + 4 𝐾 + 1 𝑃 4 ] βˆ’ 1 2 92895
(9)KRASTMPyP41 : 2 [ 𝑄 + 4 𝐾 + 2 𝑃 4 ] βˆ’ 1 1 113620