Review Article

Impact of Salmonella enterica Type III Secretion System Effectors on the Eukaryotic Host Cell

Figure 3

Effects of T3SS1 effectors on epithelial tight junctions. T3SS1 effectors SipA, SopB, SopE, and SopE2 contribute to disruption of tight junction by decreasing the amounts of ZO-1 (ZO) and phosphorylated occludin. In contrast, AvrA is a tight junction stabilizer.
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