| | Effector | Localization | T3SS | Activity | Cellular targets | Pathway/cellular process |
| | AvrA | SPI1 | 1 | Acetyltransferase
Deubiquitinase | -catenin, ERK2, IB, MKK4, MKK7, p53 | Antiapoptotic, anti-inflammatory | | CigR | SPI3 | 2 | | | | | GogB | Gifsy-1 | 2 | | FBXO22 | Anti-inflammatory | | GtgA | Gifsy-2 | 2 | | | | | GtgE | Gifsy-2 | 1/2 | Protease | | Prevents recruitment of Rab29 | | PipB | SPI5 | 2 | | | | | PipB2 | | 1/2 | | KLC (kinesin light chain) | SIF extension | | SifA | | 2 | GEF | Rab7, RhoA, SKIP | SIF, SIST, SCV formation | | SifB | | 2 | GEF | | | | SipA/SspA | SPI1 | 1 | | Caspase-3, F-actin, T-plastin | Actin assembly, disruption of tight junctions, PMN migration, SCV positioning | | SipB | SPI1 | 1 | | Caspase-1 | Pyroptosis | | SipC/SspC | SPI1 | 1 | | Cytokeratin 8, cytokeratin 18, Exo70,
F-actin, syntaxin 6 | Actin nucleation, SCV maturation | | SipD/SspD | SPI1 | 1 | | | | | SlrP | | 1/2 | E3 ubiquitin ligase | ERdj3, Trx | Apoptosis | | SopA | | 1 | E3 ubiquitin ligase | Caspase-3, HsRMA1, UbcH7 | Invasion, escape from SCV, PMN migration | | SopB/SigD | SPI5 | 1 | Phosphoinositide phosphatase/GDI | Cdc24, Cdc42 | Invasion, nuclear responses, SCV maturation, fluid secretion | | SopD | | 1/2 | | | Invasion, inflammation, fluid secretion | | SopD2 | | 2 | | | Inhibition of LNT formation | | SopE | SopE | 1 | GEF | Cdc42, Rab5, Rac1 | Actin remodeling, inflammation | | SopE2 | Phage remnant | 1 | GEF | Cdc42, Rac1 | Actin remodeling, inflammation | | SpiC/SsaB | SPI2 | 2 | | Hook3, TassC | Inhibition of fusion of SCV with lysosomes | | SptP | SPI1 | 1 | GAP
Tyrosine phosphatase | Cdc42, Rac1, VCP, vimentin | Reversion of actin reorganization, inhibition of ERK activation | | SpvB | Plasmid | 2 | Actin ribosyltransferase | G-actin | Actin depolymerization, delayed cytotoxicity | | SpvC | Plasmid | 1/2 | Phosphothreonine lyase | ERK2 | Inactivation of MAPK | | SpvD | Plasmid | 1/2 | | | | | SrfJ | Iol island | 2 | | | | | SseB | SPI2 | 2 | | | | | SseC | SPI2 | 2 | | | | | SseD | SPI2 | 2 | | | | | SseF | SPI2 | 2 | | Junction plakoglobin, TIP60 | SIF formation, SCV positioning | | SseG | SPI2 | 2 | | Caprin-1, desmoplakin | SIF formation, SCV positioning | | SseI/SrfH | Gifsy-2 | 2 | | Filamin A, IQGAP1, TRIP6 | Modulation of host cell migration | | SseJ | | 2 | Acyltransferase | RhoA, RhoC | Dynamics of the SCV | | SseK1 | | 2 | | | | | SseK2 | | 2 | | | | | SseK3 | Phage ST64B | 2 | | | | | SseL | | 2 | Deubiquitinase | IB, OSBP-1, talin, ubiquitin | Autophagy | | SspH1 | Gifsy-3 | 1/2 | E3 ubiquitin ligase | PKN1 | | | SspH2 | Phage remnant | 2 | E3 ubiquitin ligase | 14-3-3, AIP, BAG2, Bub3, Filamin A,
Profilin-1, Sgt1, UbcH5-Ub | | | SteA | | 1/2 | | | | | SteB | | 2 | | | | | SteC | | 2 | Kinase | | Actin meshwork | | SteD | | 2 | | | | | SteE | Gifsy-3 | 1/2 | | | |
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