Evaluation of Oral Robenacoxib for the Treatment of Postoperative Pain and Inflammation in Cats: Results of a Randomized Clinical Trial
Table 4
Selected hepatic biomarkers and hematological variables measured at study exit.
Robenacoxib
Placebo
Reference range
P value
Variable: units
Mean
SD
# Cases*
Mean
SD
# Cases*
High
Low
High
Low
Alkaline phosphatase (ALP): U/L
37.19**
26.71
0
1
46.38
42.89
2
0
6–102
0.93
Alanine aminotransferase (ALT): U/L
53.14
22.13
4
0
60.03
52.44
4
0
10–100
0.30
Aspartate aminotransferase (AST): U/L
35.03
25.25
5
0
35.48
25.73
2
0
10–100
1.0
Bilirubin: mg/dL
0.18
0.07
1
0
0.18
0.09
2
0
0.1–0.4
0.76
Hematocrit: %
37.51
5.47
5
3
37.07
5.64
0
5
29–48
0.18
Hemoglobin: gm/dL
12.04
1.61
2
4
11.84
1.64
0
2
9.3–15.9
0.12
Platelet Count***: 103/μL
290.15
107.77
3
21
306.16
105.16
4
5
200–500
0.45
Red Blood Cell Count: 106/μL
8.43
1.19
8
0
8.12
1.30
2
2
5.92–9.93
0.054
Number of cases with values higher (high) or lower (low) than reference range. ALP (). Platelet clumps were noted in several cases preventing precise determination of count and falsely decreasing the platelet number.
