Effects of Somatic Mutations in the C-Terminus of Insulin-Like Growth Factor 1 Receptor on Activity and Signaling
Figure 2
In vitro autophosphorylation activity of purified wild-type and mutant cytoplasmic domains. Enzymes () were incubated with 1 mM ATP, and autophosphorylation was measured using the coupled spectrophotometric assay. Data were recorded every 6 seconds.
