Dried Blood Spot Sampling with LC-MS Analysis for Routine Therapeutic Caffeine Monitoring in Neonates

<table class="table-group" id="tab3"><tr><td><table class="table"><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr class="thead"><td align="left" rowspan="2">Nominal conc. (ng/mL)</td><td align="center" colspan="2">1000</td><td align="center" colspan="2">20000</td></tr><tr class="thead"><td align="center">Fresh</td><td align="center">Stored</td><td align="center">Fresh</td><td align="center">Stored</td></tr><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr><td align="left">Mean conc. (ng/mL)</td><td align="center">955</td><td align="center">1034</td><td align="center">18377</td><td align="center">20054</td></tr><tr><td align="left">SD</td><td align="center">99</td><td align="center">95</td><td align="center">819</td><td align="center">1057</td></tr><tr><td align="left">CV%</td><td align="center">10.3</td><td align="center">9.2</td><td align="center">4.5</td><td align="center">5.3</td></tr><tr><td align="left">% Difference</td><td align="center" colspan="2">+8.3</td><td align="center" colspan="2">+9.1</td></tr><tr class="table-tr"><td colspan="5"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

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tab3

Table 3

Table 3: Dried Blood Spot Sampling with LC-MS Analysis for Routine Therapeutic Caffeine Monitoring in Neonates 