Seven structurally unique epitopes located on the outer surface of myelin basic protein (MBP) Isoform 1 are illustrated. The dimer group 1 combinations encompass the overlapping, epitopic pentamers DNEVF, NEVFG, EVFGE, and VFGEA coupled to QDTAV. The dimer group 2 combinations encompass the pentamers DNEVF, NEVFG, EVFGE, and VFGEA coupled to DTAVT. The dimer group 3 combinations encompass the overlapping, epitopic pentamers QDTAV and DTAVT individually coupled to PKNAW. Dimer group 1 displays epitope intervals that are 95, 87, 80, and 72 Ångströms. Dimer group 2 displays epitope intervals that are 88, 80, 72, and 64 Ångströms. Dimer group 3 displays epitope intervals that are 48 and 40 Ångströms. Dimeric IgE complexing hinges upon disruption of the overhanging oligodendrocyte membrane surface and facilitated intracellular autoantibody inflow. For serum antibody immunoassay purposes, the longer, inclusive peptide DNEVFGEA can be used together with QDTAVT and QDTAVT used together with PKNAW as all three peptides are sufficiently hydrophilic when coupled with the peptide-solubilizing construct, amino-ADOOA-ADOOA linker.