Biomarker Discovery of Pancreatic and Gastrointestinal Cancer by 2DICAL: 2-Dimensional Image-Converted Analysis of Liquid Chromatography and Mass Spectrometry
Figure 4
Discovery and validation of adipophilin as a colorectal cancer biomarker (partially changed from [16]). (a) 2DICAL images of the peak (m/z, 749; RT, 47.4 min) with coordinates RT versus patients (upper) and intensity versus patients (lower). Red indicates samples from colorectal cancer patients, and blue indicates samples from healthy controls. (b) Western blot of adipophilin and the loading control Complement C3b-α. (c) Large-scale RPPA validation of the plasma level of adipophilin using hundreds of clinical samples.
