Research Article
Comparison of Gene Expression Profiling in Sarcomas and Mesenchymal Stem Cells Identifies Tumorigenic Pathways in Chemically Induced Rat Sarcoma Model
Table 1
Pathways with higher incidence of strongly expressed genes.
| Rat MSCs | P value |
| Cell adhesion | <0.0001 | ECM-receptor interaction | <0.0001 | Cytokine-cytokine-receptor interaction | <0.0001 | Chemokine signaling | <0.0001 | Jak-STAT signaling | = 0.0004 | Wnt signaling | = 0.0224 |
| Rat Sarcomas | P value |
| DNA replication | <0.0001 | Cell cycle | = 0.0005 | Mismatch repair | = 0.0020 | Hedgehog signaling | = 0.0064 |
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