Synthesis, Urease Inhibition, Antioxidant, Antibacterial, and Molecular Docking Studies of 1,3,4-Oxadiazole Derivatives
Figure 1
Predicted conformations of the docked compounds inside the binding pocket of Jack bean urease. The large blue spheres indicate the metal pharmacophores around the two nickels (Ni+2) which shows that the metal atoms can interact in all directions. The dotted lines indicate various types of interactions of the compounds atoms with the active site residues including hydrogen bonding and aromatic interactions.
