International Scholarly Research Notices

Research Article

VEGF Is Involved in the Increase of Dermal Microvascular Permeability Induced by Tryptase

Figure 2

Effect of tryptase on the VEGF, Flt-1, and Flk-1 protein levels in HDMECs with or without APC366. HDMECs were treated with different concentrations of tryptase for 18 h in the absence or presence of APC366 (250 μg/mL). The protein levels of VEGF (a), Flt-1 (b), and Flk-1 (c) were determined by Western blot and normalized to GAPDH. The heparin control was also analyzed. ∗ 𝑃 < 0 . 0 5 compared to the group of nonaddition. # 𝑃 < 0 . 0 5 compared to the group only treated with tryptase at the same concentration.
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