The Effect of Cold Ischemia Time and/or Formalin Fixation on Estrogen Receptor, Progesterone Receptor, and Human Epidermal Growth Factor Receptor-2 Results in Breast Carcinoma
Figure 1
Histology and hormone receptor staining of a case with estrogen-receptor (ER-) positive, progesterone-receptor- (PR-) positive results in biopsy and ER-negative, PR-negative results in subsequent excision. (a) Biopsy, invasive ductal carcinoma, Nottingham Grade III, hematoxylin & eosin (400x); (b) biopsy, ER (+), Allred score 3 (400x); (c) biopsy, PR (+), Allred score 3 (400x); (d) excision, invasive ductal carcinoma, Nottingham Grade III, hematoxylin & eosin (400x); (e) excision, ER (−), Allred score 0 (400x); (f) excision, PR (−), Allred score 0 (400x).
