Research Article

Abnormal Movements of Japanese Infants following Treatment with Midazolam in a Neonatal Intensive Care Unit: Incidence and Risk Factors

Table 1

Characteristics of the infants.

Abnormal movement (+)Abnormal movement (−) 𝑃 -value

Case (male/female)9 (4/5)110 (67/43)0.34
Gestational age (weeks)a30.1 (5.8)34.3 (5.8)0.04
Apgar score 1b3.5 (1–8)7 (0–10)0.07
Apgar score 5b7 (5–9)8 (1–10)0.68
Birth weight (g)a1492 (1045)2109 (1074)0.10
Postnatal age when midazolam administration was started (days)a 17.2 (26.8)41.9 (59.3)0.25
Postconceptional age when midazolam administration was started (weeks)a 32.5 (5.0)40.1 (9.1)0.01
Body weight when midazolam administration was started (g)a1531 (961)2592 (1331)0.02
Dose of midazolam (mg·kg−1·h−1)a 0.14 (0.06)0.21 (0.10)0.05
Duration of midazolam administration (h)a 7.2 (13.3)162.3 (234.2)<0.0001

aData are expressed as mean (standard deviation).
bData are expressed as median (range).