Research Article

Prevalence of HIV-Associated Metabolic Abnormalities among Patients Taking First-Line Antiretroviral Therapy in Uganda

Table 5

Risk factors for borderline hyperglycemia.

CharacteristicsOdds ratio95% CI ๐‘ƒ valueAdjusted odds ratio95% CI ๐‘ƒ value

Male gender 0.76 0.44โ€“1.33 0.336 0.93 0.41โ€“2.12 0.855
Stavudine-based ART regimen 0.58 0.33โ€“1.01 0.055 0.50 0.27โ€“0.93 0.028
Age 1.32*1.14โ€“1.54 < 0.001 1.31 1.11โ€“1.56 0.002
ART duration 1.09 0.82โ€“1.46 0.550 โ€‰โ€‰โ€‰
Initial CD4 counts per 50โ€‰cells/ฮผL increase 0.94 0.80โ€“1.11 0.463 โ€‰โ€‰โ€‰โ€‰
ART start body weight 1.00 0.97โ€“1.03 0.95 โ€‰โ€‰โ€‰
Peak body weight > 65โ€‰kgs 1.00 0.92โ€“1.09 0.957 โ€‰โ€‰โ€‰
Enrolment BMI < 24 1.00 1.00โ€“1.02 0.213 โ€‰โ€‰โ€‰
Systolic blood pressure > 150โ€‰mm/Hg 1.02 1.00โ€“ 1.03 0.05 1.01 0.90โ€“1.03 0.146
Enrolment CD4 count > 200โ€‰cells/ฮผL 1.06 0.55โ€“2.05 0.86 โ€‰โ€‰โ€‰
Abnormal waist to hip ratio+ 1.97 1.01โ€“3.84 0.046 1.73 0.67โ€“4.46 0.255
Family history of hypertension 0.99 0.57โ€“1.73 0.972 โ€‰โ€‰โ€‰
Family history of diabetes mellitus 1.71 0.91โ€“3.22 0.095 2.18 1.10โ€“4.34 0.026
Lipodystrophy 0.98 0.56โ€“1.89 0.946 โ€‰โ€‰โ€‰โ€‰
WHO stage III and IV 1.00 0.54โ€“1.85 0.991 โ€‰โ€‰โ€‰

CI: confidence interval; ART: antiretroviral treatment; BMI: body mass index; WHO: World Health Organization.
+WHR defined abnormal if > 0.94 for males and > 0.8 for females.
*Denote that age as a variable was supposed to be interpreted as a 5-year increase as interpreted in the text.