Prevalence of HIV-Associated Metabolic Abnormalities among Patients Taking First-Line Antiretroviral Therapy in Uganda
Table 5
Risk factors for borderline hyperglycemia.
Characteristics
Odds ratio
95% CI
value
Adjusted odds ratio
95% CI
value
Male gender
0.76
0.44โ1.33
0.336
0.93
0.41โ2.12
0.855
Stavudine-based ART regimen
0.58
0.33โ1.01
0.055
0.50
0.27โ0.93
0.028
Age
1.32*
1.14โ1.54
0.001
1.31
1.11โ1.56
0.002
ART duration
1.09
0.82โ1.46
0.550
โ
โ
โ
Initial CD4 counts per 50โcells/ฮผL increase
0.94
0.80โ1.11
0.463
โ
โ
โโ
ART start body weight
1.00
0.97โ1.03
0.95
โ
โ
โ
Peak body weight 65โkgs
1.00
0.92โ1.09
0.957
โ
โ
โ
Enrolment BMI 24
1.00
1.00โ1.02
0.213
โ
โ
โ
Systolic blood pressure 150โmm/Hg
1.02
1.00โ 1.03
0.05
1.01
0.90โ1.03
0.146
Enrolment CD4 count 200โcells/ฮผL
1.06
0.55โ2.05
0.86
โ
โ
โ
Abnormal waist to hip ratio+
1.97
1.01โ3.84
0.046
1.73
0.67โ4.46
0.255
Family history of hypertension
0.99
0.57โ1.73
0.972
โ
โ
โ
Family history of diabetes mellitus
1.71
0.91โ3.22
0.095
2.18
1.10โ4.34
0.026
Lipodystrophy
0.98
0.56โ1.89
0.946
โ
โ
โโ
WHO stage III and IV
1.00
0.54โ1.85
0.991
โ
โ
โ
CI: confidence interval; ART: antiretroviral treatment; BMI: body mass index; WHO: World Health Organization.
+WHR defined abnormal if 0.94 for males and 0.8 for females.
*Denote that age as a variable was supposed to be interpreted as a 5-year increase as interpreted in the text.