Implication of DNA Methylation Profiling in Oral Epithelium for
Lung Cancer Screening
Figure 1
Methylation of GDNF, RARB, and HS3ST2 genes in oral epithelium. Methylation-specific PCR amplification of the GDNF (a), RARB (b), and HS3ST2 (c) genes using unmethylation-specific (U) and methylation-specific (M) primers were performed with DNA isolated from oral epithelium. Aberrant methylation was detected in patients 1, 2, and 3 (arrows).
