Clinical Study

The Effects of Continuous Blood Purification for SIRS/MODS Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Table 1

Baseline characteristics of the included studies.

TrialsSample
size ( )
CountryDiseaseIllness severity scores AgeFilter membraneBlood flow (mL/min)Treatment

Sander 1997 [6]13/13GermanySIRS AN69150 mL/minCVVH* versus control
Sanchez Riera 1997 [7, 8]15/15SpainMODS A AN69130 mL/minCVVH* versus control
Cole et al. 2002 [9]12/12AustraliaMODS AMedian (IQR) 65.5 (22.0)/
68.0 (19.0)
AN69200 mL/minCVVH* versus control
Liu et al. 2003 [10]24/26ChinaMODS A AN69 +PS200–250 mL/minCVVH* versus control
Yang et al. 2004 [11]22/15ChinaSIRS A PS150–200 mL/minCVVH* versus control
Ding and Zhao 2007 [12]11/10ChinaMODS A23–78/23–78PSNot reportedCVVH* versus control
Yang and Hoyang 2008 [13]31/27ChinaSIRS A PS180–250 mL/minCVVH* versus control
Peng et al. 2008 [14]17/15ChinaSIRS A28–70/30–69AN69250–300 mL/minCVVH* versus control
Zhang et al. 2006 [15]30/30ChinaSIRSNot reported PS150–200 mL/minCVVH* versus control
Payen et al. 2009 [16]37/39FranceSIRS B PS150 mL/minCVVH* versus control

MODS: multiple-organ dysfunction syndrome.
SIRS: systemic inflammatory response syndrome.
CVVH* group: CVVH + conventional therapeutic measures.
Control group: conventional therapeutic measures.
A: acute physiology and chronic health evaluation, APACHE II score; B: simplified acute physiology score, SOFA score.