Clinical Study
The Effects of Continuous Blood Purification for SIRS/MODS Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Table 1
Baseline characteristics of the included studies.
| Trials | Sample size () | Country | Disease | Illness severity scores | Age | Filter membrane | Blood flow (mL/min) | Treatment |
|
Sander 1997 [6] | 13/13 | Germany | SIRS | | | AN69 | 150 mL/min | CVVH* versus control |
Sanchez Riera 1997 [7, 8] | 15/15 | Spain | MODS |
A | | AN69 | 130 mL/min | CVVH* versus control |
Cole et al. 2002 [9] | 12/12 | Australia | MODS |
A | Median (IQR) 65.5 (22.0)/ 68.0 (19.0) | AN69 | 200 mL/min | CVVH* versus control |
Liu et al. 2003 [10] | 24/26 | China | MODS |
A | | AN69 +PS | 200–250 mL/min | CVVH* versus control |
Yang et al. 2004 [11] | 22/15 | China | SIRS |
A | | PS | 150–200 mL/min | CVVH* versus control |
Ding and Zhao 2007 [12] | 11/10 | China | MODS |
A | 23–78/23–78 | PS | Not reported | CVVH* versus control |
Yang and Hoyang 2008 [13] | 31/27 | China | SIRS |
A | | PS | 180–250 mL/min | CVVH* versus control |
Peng et al. 2008 [14] | 17/15 | China | SIRS |
A | 28–70/30–69 | AN69 | 250–300 mL/min | CVVH* versus control |
Zhang et al. 2006 [15] | 30/30 | China | SIRS | Not reported | | PS | 150–200 mL/min | CVVH* versus control |
Payen et al. 2009 [16] | 37/39 | France | SIRS |
B | | PS | 150 mL/min | CVVH* versus control |
|
|
MODS: multiple-organ dysfunction syndrome. SIRS: systemic inflammatory response syndrome. CVVH* group: CVVH + conventional therapeutic measures. Control group: conventional therapeutic measures. A: acute physiology and chronic health evaluation, APACHE II score; B: simplified acute physiology score, SOFA score.
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