Clinical Study
Pharmacoeconomics and Pharmacodynamic Interactions of Rocuronium and Pancuronium
Table 2
Comparison of hemodynamic changes following administration of muscle relaxant.
| | Hemodynamic parameters | Group R (n = 20) | Group P (n = 20) | Group C (n = 20) | Between group comparison P value |
| | Heart rate (beats/min) | | | | | | Baseline | 86.42 ± 4.11 | 90.05 ± 4.45 | 89.86 ± 3.87 | 0.77 | | 1 min PIT | 98.32 ± 3.3* | 103.85 ± 3.6* | 98.48 ± 3.4* | 0.42 | | 5 min PIT | 89.05 ± 3.7 | 94.15 ± 4.5 | 88.30 ± 3.8 | 0.48 | | P value | 0.000 | 0.005 | 0.004 | |
| | SBP (mm Hg) | | | | | | Baseline | 127.47 ± 2.5 | 127.00 ± 4.9 | 130.19 ± 2.7 | 0.73 | | 1 min PI | 108.63 ± 3.5* | 105.65 ± 3.0* | 108.38 ± 4.1* | 0.77 | | 1 min PIT | 125.68 ± 4.5 | 125.55 ± 3.8 | 123.29 ± 3.2 | 0.86 | | 5 min PIT | 109.05 ± 2.7* | 109.30 ± 3.6* | 111.80 ± 2.9* | 0.75 | | P value | 0.000 | 0.000 | 0.000 | |
| | DBP (mm Hg) | | | | | | Baseline | 79.37 ± 1.7 | 78.25 ± 3.2 | 81.43 ± 1.5 | 0.54 | | 1 min PI | 65.63 ± 3.7* | 63.25 ± 3.9* | 67.81 ± 3.3* | 0.59 | | 1 min PIT | 79.79 ± 3.7 | 78.40 ± 3.6 | 79.19 ± 2.5 | 0.94 | | 5 min PIT | 68.63 ± 3.1* | 69.30 ± 3.2* | 70.85 ± 2.5* | 0.82 | | P value | 0.000 | 0.001 | 0.000 | |
|
|
Comparison to baseline.
|
